github link
Accession IconE-MTAB-2610

Expression profiling in four human bladder cancer cell lines

Organism Icon Homo sapiens
Sample Icon 11 Downloadable Samples
Technology Badge Icon Affymetrix Human Genome U133A Array (hgu133a)

Submitter Supplied Information

Description
To identify miRNA-target interactions that are important in bladder cancer metastasis, we profiled miRNA and mRNA expression in poorly metastatic cell lines T24 and LUC, and their metastatic derivatives FL4 and LUL2, respectively. We reasoned that miRNAs and genes that expressed differently between parental and derivative cell lines could potentially contribute to their disparity in metastatic competence. We further hypothesized that interactions between these miRNAs and target genes may play an important role in metastatic competence. We have developed the multiMiR R pacakge and database for such integrated analysis of miRNA-target interactions. Here we demonstrate how multiMiR was used to generate testable hypotheses that could be pursued experimentally. The data set here is from the mRNA expression profiling experiment. Please see E-MTAB-2611 ( <a href="https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-2611/" target="_blank">https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-2611/</a> ) for the microRNA profiling data set.
PubMed ID
No associated PubMed ID
Total Samples
11
Submitter’s Institution
Authors
No associated authors
Source Repository

Samples

Show of 0 Total Samples
Filter
Add/Remove
Accession Code
Title
Specimen part
Cell line
Processing Information
Additional Metadata
No rows found
Loading...