Depletion of Erk1 and Erk2 MAP kinases in primary human keratinocytes

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GSE15417

Homo sapiens

9 Downloadable Samples

Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Submitter Supplied Information

Description

We assessed the effect of RNAi-mediated MAP kinase cascade signaling blockade in primary human keratinocytes. Two sets of siRNA targeting different regions of the Erk1/2 genes were used, enabling identification of off-target siRNA effects.

PubMed ID

19414607

Publication Title

Erk1/2 MAP kinases are required for epidermal G2/M progression.

Total Samples

Submitter’s Institution

University of California, San Francisco

Authors

Dumesic PA, Scholl FA, Barragan DI, Khavari PA

Source Repository

Gene Expression Omnibus (GEO)

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