Fine mapping of androgen regulated genes in LNCaP cells

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GSE18684

Homo sapiens

96 Downloadable Samples

Illumina human-6 v2.0 expression beadchip

Submitter Supplied Information

Description

Detailed analysis of androgen regulated gene expression in the LNCaP prostate cancer cell line. Since androgens and the AR are known to be important for prostate cancer cell proliferation and invasion we aimed to identify androgen receptor (AR) regulated genes by combining this detailed Illumina beadarray study of androgen regulated gene expression with AR ChIP-sequencing data.

PubMed ID

21602788

Publication Title

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis.

Total Samples

Submitter’s Institution

Cambridge University and Cancer Research UK

Authors

Massie CE, Lynch A, Ramos-Montoya A, Boren J, Stark R, Fazli L, Warren A, Scott H, Madhu B, Sharma N, Bon H, Zecchini V, Smith DM, Denicola GM, Mathews N, Osborne M, Hadfield J, Macarthur S, Adryan B, Lyons SK, Brindle KM, Griffiths J, Gleave ME, Rennie PS, Neal DE, Mills IG

Source Repository

Gene Expression Omnibus (GEO)

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