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Accession IconGSE26506

Genomic Analysis of Individual Differences in Ethanol Drinking: Evidence for Non-genetic Factors in C57BL/6 Mice

Organism Icon Mus musculus
Sample Icon 57 Downloadable Samples
Technology Badge Icon Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

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Here, we identify persistent and substantial variation in ethanol drinking behavior within an inbred mouse strain and utilize this model to identify gene networks influencing such non-genetic variation in ethanol intake. C57BL/6NCrl mice showed persistent inter-individual variation of ethanol intake in a two-bottle choice paradigm over a three week period, ranging from less than 1 g/kg to over 14 g/kg ethanol in an 18h interval.
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