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Accession IconGSE34602

Expression data from 3 gamma-secretase or mock-treated mantle cell lymphoma (MCL) cell lines

Organism Icon Homo sapiens
Sample Icon 11 Downloadable Samples
Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

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Description
We identified recurrent NOTCH1 mutations in 12% of MCLs. 2 out of 10 tested MCL cell lines (Rec-1 and SP-49) were sensitive to inhibition of the NOTCH pathway by gamma-secretase inhibition.
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12
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